Onuplat

Onuplat

Onuplat, used in combination with infusional 5-fluorouracil/leucovorin, is indicated for

  • Adjuvant treatment of stage III colon cancer in patients who have undergone complete resection of the primary tumor.
  • Treatment of advanced colorectal cancer.
  • Gastric Cancer
Break the
              Vicious Growth Circle

Expert's View

  • The SOX regimen - a neoadiuvant chemotherapy for advanced gastric cancer worldwide in the future.
  • SOX is as effective as CS for AGO with favorable safety profile, therefore SOX can replace CS.
  • SOX regimen could be an alternative first-line doublet chemotherapy strategy for patients with metastatic colorectal cancer.
  • Oxaliplatin has recently been approved for treating unresectable advanced or recurrent gastric cancer.
  • The combination of PTX combined with 0XA is an active and safe regime for AGC and has a high overall response rate.
  • Oxaliplatin can bypass canonical cell death pathways to kill gastric cancer cells, which may be of therapeutic advantage in the treatment of gastric cancer.
  • Adjuvant capecitabine plus oxaliplatin treatment after curative D2 gastrectomy should be considered as a treatment option for patients with operable gastric cancer.
  • Combination chemotherapy with SOX offers an effective, safe and well-tolerated regimen for elderly patients with advanced gastric cancer.