Mozotize
Indicated for the treatment of
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Newly diagnosed glioblastoma multiforme (GBM) concomitantly with radiotherapy and then as maintenance treatment.
- Refractory anaplastic astrocytoma patients who have experienced disease progression on a drug regimen containing nitrosourea andvProcarbazine.
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Expert's View
- The combination of capecitabine and temozolomide has emerged as the most promising and efficacious treatment in Neuroendocrine tumors . The oral route of administration and the substantial improvement in the outcomes with manageable toxicity are the major advantages
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CAPTEM is highly active, well tolerated and may prolong survival in patients with well-differentiated, metastatic NET ( metastatic neuroendocrine tumors )
- In recurrent GBM, temozolomide compared with standard chemotherapy improves time-to-progression (TTP) and may have benefits on QoL without increasing adverse events but it does not improve overall.
- Temozolomide when given in both concomitant and adjuvant phases is an effective primary therapy in GBM compared to radiotherapyalone.
